We also showed, for the first time, that GLP-1Rs are expressed primarily on GABA neurons in the VTA and that the suppressive effects of a GLP-1R agonist on cocaine seeking are associated with increased activity of VTA GABA neurons and decreased activity of VTA dopamine neurons
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Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer
Some patients achieve target weight loss at lower doses, while others require maximum dosing for optimal results
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