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Vitamin B5 can lead to eosinophilic pleuropericarditis and patients should be checked if they have a history of allergies to it
Treatment with once-weekly cagrilintide (0.16, 0.30, 0.60, 1.2, 2.4, and 4.5 mg) in combination with semaglutide 2.4 mg for 20 weeks was not associated with an increase in adverse events compared with placebo in combination with semaglutide 2.4 mg, with no unexpected safety or tolerability findings
Data is nascent, and combination approaches will necessitate close monitoring for hormonal equilibrium and metabolic adverse effects
The committee will evaluate whether sufficient safety and efficacy evidence exists to make compounded peptides available legally throughout the U.S