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Clinical Note: While medication provides a biological mute button, a 2025 systematic review notes that these tools work best as a support to existing additions like therapy and nutritional support

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Over-the-counter antacids or H2 blockers may provide relief, but consult your provider before starting any new medication

Nitric oxide is a vasodilator, meaning it helps relax and widen blood vessels, improving blood flow

GLP-1 receptor agonists were associated with reduced diabetic foot ulcer and lower limb amputation risk in retrospective cohort studies