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First, a missed dose : the documented handling is to take it as soon as reasonably possible if several days remain before the next scheduled dose, otherwise skip it never double up to compensate, because two doses close together stacks the incretin effect and reliably provokes GI symptoms

We do not want the blood and mucous hardening and scabbing

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doi:10.1038/sj.ijir.3901139 (source) Rosen RC, Diamond LE, Earle DC, Shadiack AM, Molinoff PB