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Recently, Pescosolido and colleagues [161] evaluated the presence of carnitine in tears of dry eye patients and suggested that the damage incurred on the ocular surface of dry eye patients may, in part, be due to a lack of carnitine in the tear film of these patients relative to the ocular surface cells and suggested use of solutions containing carnitine to reduce this damage
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At the same time, increased expression of BBD and OCTN2 also plays a role in regulating carnitine homeostasis by stimulating the intake and biosynthesis of the carnitine, thus increasing the concentration of carnitine (86)
