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In my experience, clients see benefits with anxiety, insomnia, menstrual cramps, and even migraines/headaches, within the first week

The weight loss can also lighten the load on hips and knees, and the drugs may help protect kidneys, too

International Journal of Molecular Sciences 26 (4)

Additional increases to 70 mg/day were made as tolerated and clinically indicated

Clinical context on this medication class (for informational purposes only): In clinical trials involving FDA-approved branded medications, both semaglutide and tirzepatide have produced meaningful average weight-loss results in specific study populations