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Moreover, the stepwise administration of amylin and GLP-1R analogs was able to break the plateau normally observed with individual pharmacotherapies, even when combined from the beginning of treatment, thus supporting the hypothesis that a stepwise-introduction of a combinatorial pharmacological approach at treating obesity is more effective in achieving a sustained and long-lasting degree of weight loss

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For ideal oral hygiene and effective management of this potential side effect, individuals should limit dehydrating substances such as coffee and alcohol

This outcome can be explained by the substantial weight loss and malabsorption that can follow bariatric surgery (6, 18, 20, 2325)