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In addition, there was a trend for decrease for all cohorts in mean systolic and diastolic blood pressure similar to placebo
The incidence of diarrhoea was significantly higher in the metformin group at weeks 4 ( p = 0.003) and 8 ( p = 0.01), but no longer at week 16
Tamoxifen changed how breast cancer is treated and prevented and became a corner stone of care for ER+ patients
The treatment may also incorporate nutrients that support estrogen metabolism and liver detoxification pathways
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