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Protects and strengthens bone, increasing bone formation and mineral density

In the late 1990s, researchers at Yale University observed a rapid antidepressant response to a single, subanesthetic intravenous infusion of ketamine, which ignited a plethora of research that has established the effectiveness of ketamine, esketamine (FDA approved as intranasal Spravato in 2019), and dextromethorphan (FDA approved in 2022 as Auvelity, a combination of dextromethorphan/bupropion) as rapid-acting antidepressants

Glutathione is present in a ratio of both oxidized and reduced forms, but both are protective

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One of the most common physiological changes seen is the depletion of the body's most powerful antioxidant, reduced glutathione