Artesunate was shown to inhibit apoptosis and promote survival in Schwann cells via the PI3K/Akt/mTOR axis in DPN (Zhang et al., 2023)
In vitro studies using endothelial cell models have demonstrated effects on fibroblast migration rates, endothelial cell tube formation in angiogenesis assays, and cytoprotective mechanisms in cell culture models exposed to oxidative and chemical stressors
The Ca2+/Calmodulin-dependent protein kinase kinase, Camkk2, inhibits preadipocyte differentiation
[41] Almeida, E.B., Santos, J.M.B., Paixo, V., Amaral, J.B., Foster, R., Sperandio, A
Target Screen of Anti-Hyperuricemia Compounds from Cortex Fraxini In Vivo Based on ABCG2 and Bioaffinity Ultrafiltration Mass Spectrometry