An often-used term for symptoms, for which no explanation is found, is medically unexplained symptoms
The review confirmed that NNMT-mediated NAD+ depletion impairs mitochondrial function, SIRT activity (particularly SIRT1 and SIRT3), redox balance, and energy metabolism, creating conditions relevant to cardiovascular disease research models
Furthermore, IM administration of hydroxocobalamin is also the preferred treatment for pediatric patients with intrinsic cobalamin metabolic diseases
However, it's easy to avoid vitamin B12 deficiency by recognizing if you're at risk and taking measures to avoid developing a deficiency
Vitamin B12 is water-soluble, meaning your body eliminates excess through urine rather than storing it to potentially toxic levels