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The two pathways converge on somatotroph calcium signaling but engage different second-messenger cascades, which is why the combination can produce more GH than either agent alone
He Y, Guo X, Tan B, Dong X, Yang Q, Liu H, Zhang S, Chi S (2021
Inhibition of the Trx system by auranofin induced cell death (most likely ferroptosis) only in non-endocrine small cell lung cancer, whereas inhibition of the Grx system by buthionine sulfoximine killed specifically the endocrine cells [203]
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