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[Polarography of glutathione in physiological media

Toxicol Appl Pharmacol 242 ,241-246 (2010)

The reduced form of glutathione is the bioactive form

Furthermore, GSTs are additionally identified as regulators of cellular signaling pathways, thereby influencing cell proliferation or apoptosis ( in vitro with chemically reactive metabolites derived from several drugs displaying idiosyncratic toxicity, including troglitazone, acetaminophen, clozapine, and diclofenac ( HepG2 cells have been used for decades as a test system for studies involving hepatotoxic compounds

Catalytic and regulatory properties of the heavy subunit of rat kidney gamma-glutamylcysteine synthetase