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The combination of phentermine, a psychostimulant, and topiramate, a carbonic anhydrase inhibitor, has been associated with increased heart rate (Alfaris 2015)

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These medicines include: Rare cases of drug-induced vitiligo have also been reported from: Note: phenols that cause localised contact leukoderma, such as monobenzyl ether of hydroquinone, paraphenylenediamine and rhododendrol, may also cause generalised vitiligo in rare cases

2 capsules once daily