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The mean complete PRO score was 2 (range 0-3, Standard Deviation [SD] 1.1), out of a maximum score of 15-16, depending on the applicability of proxy-reporting items

Dose Range: 5001,500 mcg total blend daily (providing ~250750 mcg of each peptide)

For add-back experiments, recombinant xPAF15 was added to xPAF15-depleted extracts at 320 nM, recombinant xUHRF1 was added to xUHRF1-depleted extracts at 110 nM, and recombinant xDNMT1 was added to xDNMT1-depleted extracts at 85 nM

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