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To date, available clinical experience primarily derived from populations with T2DM or obesity receiving concomitant immunomodulatory therapies has not revealed major safety signals related to increased infection risk or immune suppression

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In Summary GLP-1 medications can be helpful for someone who is struggling to lose weight or has weight loss resistance, however they are not a replacement for changing behaviors

IMD-0354 could disrupt the membrane localization of ASCT2 and attenuate mTOR signaling