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Mitochondria are metabolic centers of cellular energy, providing sufficient energy for cells through a series of metabolic mechanisms, including the tricarboxylic acid (TCA) cycle and oxidative phosphorylation (OXPHOS) [11]

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At the genomic level, Epitalon modulated the expression of key circadian rhythm genes: Clock expression in leukocytes decreased 1.8-fold, Cry2 expression doubled, and Csnk1e expression in lymphocytes decreased by 2.1-fold, all with statistical significance

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