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Potential Causes of Allodynia Allodynia is associated with several neurological and metabolic conditions, including: Peripheral Neuropathy (due to diabetes, chemotherapy, or autoimmune disorders) Fibromyalgia (central pain sensitisation disorder) Migraine Disorders (involving trigeminal nerve hypersensitivity) Neuroinflammation and Immune Dysregulation (as seen in post-viral syndromes) Medication Side Effects, including possible links to GLP-1 receptor agonists Mechanisms: How GLP-1 Medications May Contribute to Allodynia GLP-1 receptor agonists (e.g., Mounjaro, Wegovy) are widely used for weight loss and glycemic control due to their role in glucose-dependent insulin secretion and appetite suppression

This dual action creates an environment where the bodys fat stores are mobilized and less likely to accumulate

The pelvic floor muscles support the urinary sphincter, so as the muscles grow weaker, the urethra loses its ability to hold in urine

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