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Obesity itself significantly impairs testosterone production, and weight loss typically improves hormonal profiles rather than impairing them

The success of medical weight loss depends on how well the patient responds to the medication, as it is possible for patients to experience adverse side effects or be unable to efficiently increase the dosage of the medication safely

UHCs typical prior authorization requirements for Wegovy and Zepbound include: BMI documentation A documented BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related comorbidity such as type 2 diabetes, hypertension, dyslipidemia, or obstructive sleep apnea Comorbidity evidence Clinical records documenting the specific comorbidities that support the medical necessity of treatment Supervised weight management history Evidence of participation in a structured weight management program, which may include diet, exercise, and behavioral counseling, typically for 3 to 6 months prior to the request Prescriber qualifications The prescriber must be a physician, nurse practitioner, or physician assistant with appropriate prescribing authority UHC reviews prior authorizations against specific clinical policy bulletins

2022;39(6): e14821

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