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OWL833, an orally active nonpeptide GLP-1 receptor agonist, improves glucose tolerance by increasing insulin secretion and reduces food intake of cynomolgus monkeys

Weight changes and fat redistribution during menopause can increase insulin resistance, which is a factor in Type 2 diabetes adding testosterone therapy might further increase the risk

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The crossover study of an oral methionine load by Bellamy et al (1998) also supports the view that elevated homocysteine levels may promote vascular disease by impairing flow-mediated endothelium dependent vasodilation