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Functioning as a potent exercise mimetic, this small-molecule compound enhances mitochondrial function, fatty acid oxidation, and oxidative muscle fiber composition, thereby improving exercise endurance, cardiac metabolic efficiency, and systemic energy expenditure without increasing food intake 1-4
Mol Cell Endocrinol 297:3440 Mukai E, Fujimoto S, Sato H, Oneyama C, Kominato R, Sato Y, Sasaki M, Nishi Y, Okada M, Inagaki N (2011) Exendin-4 suppresses Src activation and reactive oxygen species production in diabetic Goto-Kakizaki rat islets in an Epac-dependent manner
In this exclusive conversation, he shares the inspiration behind his work, the science of glutathione, and the future of antioxidant therapy
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