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Which areas of the body can be treated with skin tightening

Clinical protocols typically involve 2-5 mg doses twice weekly for the first month, followed by maintenance dosing

According to the NICE Clinical Knowledge Summary (CKS) and the British National Formulary (BNF) , the standard treatment for B12 deficiency without neurological symptoms involves: Hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks Followed by maintenance doses of 1 mg every three months For patients with neurological symptoms (such as paraesthesia, numbness, cognitive changes, or gait disturbances), more intensive treatment is required: Hydroxocobalamin 1 mg intramuscularly on alternate days until no further improvement occurs Followed by 1 mg every two months for maintenance Pernicious anaemia , an autoimmune condition where the body cannot produce intrinsic factor, requires lifelong treatment

Combined protocols should be limited to 6 to 8 weeks maximum followed by equal or greater rest periods

Use appropriate syringes and needles (typically 4-6mm length, 31-32 gauge for subcutaneous delivery)