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Women have lower average body mass, different fat distribution, different hepatic enzyme activity, and a hormonal environment that interacts with metabolic medications in ways most original trial protocols don't fully account for

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In 2022, the CDC reported that more than 716,000 obesity-associated cancers occurred in the United States

133 Fasting GIP levels are also higher in T2DM patients, 134 although there is no significant difference in postprandial GIP levels

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