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We know that optimal glycemic control is the foundation of good diabetes care, but it's not going to be the solution to preventing kidney disease, Tuttle said

Adherence to titration schedule : Deviating from the prescribed escalation plan may blunt the therapeutic response

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We have to be careful about using them willy-nilly, like with someone, for example, who has a normal BMI and may just not be happy because of a slight increase in body weight, says Chervenak