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Research indicates that although semaglutide did not significantly improve hepatic fibrosis, it had positive effects on hepatic steatosis, weight control, and diabetes-related parameters, offering a new therapeutic direction for patients with NASH and compensated cirrhosis (Flint et al., 2021
On the other hand, an elevated concentration of homocysteine, and its metabolites such as homocysteine thiolactone and N-homocysteinyllysine result in health problems and has been indicated as an independent risk factor for cardiovascular disease and accelerated atherosclerosis
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The peptide also demonstrates anti-inflammatory effects without the negative side effects associated with corticosteroid injections
Therefore, further investigation is warranted to elucidate the underlying mechanisms
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