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Tumor cells are especially vulnerable to ROS-based therapies due to their limited antioxidant defenses

Flavonoids can also interfere with the activation of transcription factors, such as nuclear factor-kappa B (NF-B) and activator protein-1 (AP-1) which regulate the expression of various pro-inflammatory genes (Yoon and Baek 2005)

Cao, Y., Yi, W., & Zhu, Q