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BH3 peptides/mimetics in DTEP buffer (300 mM trehalose, 10 mM HEPES-KOH, 0.1% w/v BSA, 1 mM EDTA, 1 mM EGTA, 80 mM KCl, 5 mM succinate, final pH 7.4) were plated at 70 M l 1 (unless otherwise stated) in triplicate in a black 384-well plate

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These cells, along with pathogens and cancer cells, ingest excess heme-iron, oxidize proteins and cholesterol, form clots, and build new blood vessels

We observed higher levels of stage 1 and 2 DAM marker genes, the inflammatory marker il1b (Fig