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Specifically, these two myokines are considered protective proteins released from muscle in response to exercise and are particularly important in responding to oxidative stress and maintaining mitochondrial function [39, 89]
Researchers have already tested a range of doses and escalation schedules, providing valuable insight into how treatment may start, increase, and be maintained
A 2019 safety review examined 87 human studies on natural astaxanthin including 35 using doses of 12mg per day or higher and found no significant safety concerns or consistent adverse effects.11 Across those trials, approved or studied doses commonly ranged between 2mg and 24mg per day, and higher short-term doses (up to 40mg per day for several weeks) have also shown good tolerability in adults, with no serious events reported
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