However, hyperuricemic patients with varying degrees of ABCG2 dysfunction, categorized by genotypes of dysfunctional SNPs, exhibit hyperuricemia characterized by urate overproduction
The most common side effects are gastrointestinal, with nausea occurring in 15-44% of patients, followed by vomiting, diarrhea, constipation, and abdominal discomfort
Sun LL, Wan XX, Zhang Y, Zhang YH, Zhao WJ, Wang D, et al
Mild to moderate gastrointestinal side effects don't indicate harm and typically signal that the medication is working effectively
doi: 10.1016/j.nutres.2010.04.004 7