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Obesity, particularly in those with android body fat distribution, are at increased risk of NAFLD and disease progression and individuals with complications such as hypertension, knee osteoarthritis, or sleep apnea should also be screened for advanced liver disease
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Nature 472 , 5763 (2011)
The compound has been shown in cell-based research to upregulate VEGFR2 transcript levels, increase phosphorylation of downstream signalling intermediates after VEGF stimulation, and enhance endothelial tube formation in matrigel assays
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