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Goal: Support significant weight reduction and metabolic improvements through triple-receptor activation [1] [7]
The investigation assessed DNA damage caused by bile exposure by measuring the ROS marker 8-oxo guanine and performing comet assays
[1] These were recreationally active men with VO2 max of 49.8 6.6 mL/kg/min
Abbreviations ESKD: End-stage kidney disease GLP-1 RA: Glucagon-like peptide-1 receptor agonist HF: Heart failure ICER: Incremental cost-effectiveness ratio MI: Myocardial infarction NDSS: National Diabetes Services Scheme QALY: Quality-adjusted life year SGLT2i: Sodiumglucose co-transporter 2 inhibitor References McGuire DK, Shih WJ, Cosentino F et al (2021) Association of SGLT2 inhibitors with cardiovascular and kidney outcomes in patients with type 2 diabetes: a meta-analysis
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