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In phase 2 clinical trials published in the New England Journal of Medicine (2023), it demonstrated substantial weight loss outcomes, largely attributed to its ability to influence hunger signals particularly in the hypothalamus, which governs satiety and energy balance

This new CPMMH regimen was protective of the UB without any CP-induced HC damage under antioxidant, anti-inflammatory, and antifibrotic actions (Mousa et al., 2022)

When to Talk to a Specialist If youre experiencing fatigue, low libido, weight gain, or reduced muscle mass, a full hormone and metabolic evaluation can help determine the cause

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For guidance on managing this, our resource on GLP-1 constipation relief strategies offers practical solutions that apply to probiotic-induced constipation as well