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Li H, Sun T, Liu C, Cao Y, Liu X

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In clinical trials, weekly subcutaneous semaglutide at the 2.4 mg dose (the Wegovy formulation) produced a mean weight loss of approximately 14.9% of body weight over 68 weeks in the STEP 1 trial, compared with 2.4% for placebo

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However, resmetirom and semaglutide differ significantly in their mechanisms of action, metabolic effects, safety profiles, and potential clinical applications

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