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A systematic review and meta-analysis published in 2020 found that liraglutide treatment resulted in significant reductions in body weight (mean difference approximately 4-5 kg compared to placebo or metformin), improved insulin sensitivity markers, and favourable changes in lipid profiles

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Rademakers, TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics

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The risk emerges when the use case shifts toward human administration without following IND protocols or when sourcing lacks the purity verification and intended-use documentation required to demonstrate research intent