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Until recently, fascia was largely ignored in knee OA research, but new discoveries in the 2020s show that fascial structures play critical roles in knee pain, stiffness, biomechanics, and knee OA progression

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Thirdly, we synthesize the metabolisminflammationendocrinemicrobiota interaction to offer new insights into multi-target therapies, suggesting that restoring gut homeostasis may be a critical strategy for improving endometrial quality

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