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R.GaryS.et al (2008)

The most significant effect of the MT 1 and MT 2 receptors to phase shift local and overt circadian rhythms

Epitalon has been shown to significantly increase the expression of key antioxidant enzymes: Superoxide dismutase (SOD-1) Catalase NAD(P)H quinone dehydrogenase 1 (NQO1) These effects are mediated via the Keap1/Nrf2 signaling pathway [40, 41]: a master regulator of cellular redox balance

Plays a Role in Heart Health Glutathione supports cardiovascular health by reducing oxidative stress and helping maintain healthy blood vessels

5-Amino-1MQ is a small-molecule compound and selective inhibitor of NNMT (Nicotinamide N-methyltransferase), an enzyme involved in regulating NAD+ metabolism and one-carbon pathway signalling