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"Centenarians display plasma MOTS-c concentrations significantly higher than age-matched peers, a pattern that closely resembles levels found in individuals decades younger suggesting preserved mitochondrial signaling as a hallmark of exceptional longevity." The connection to cellular senescence deserves further attention here
A 2018 review in the International Journal of Molecular Sciences analyzed available gene expression data and found that GHK-Cu at clinically relevant concentrations affected the expression of approximately 31.2% of human genes [2]
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Read More Iron that is too high or too low adversely affects cardiovascular health
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