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Vitamin B12, or cobalamin, is a water-soluble vitamin
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The drug or biologic administered is billed separately using the appropriate HCPCS Level II J-code (e.g., J0290 for ampicillin, J1040 for methylprednisolone, J0135 for adalimumab)
While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control
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