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The NIH/PMC systematic review on BPC-157 in orthopaedic sports medicine found that preclinical studies indicate its potential for promoting healing in musculoskeletal injuries including fractures, tendon ruptures and ligament tears, and noted that in one retrospective observation involving intraarticular injection for chronic knee pain, 7 of 12 patients reported relief for more than 6 months

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It supports cellular migration and organization during repair, which is why it is commonly used as a model compound in wound-healing and regenerative research