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doi: 10.1016/j.freeradbiomed.2017.07.028 49 HeinigRFrickeRWertzSNagelschmitzJLoewenS

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Jordi Fernndez Lpez Licenciado en Educacin Fsica y Deportes

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GLP-1 receptor agonists exert their therapeutic effects through several mechanisms : they stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, suppress glucagon release (which reduces hepatic glucose production), slow gastric emptying, and act on appetite centres in the hypothalamus to promote satiety and reduce food intake

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