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This intracellular gliotoxin activates the transcription factor GliZ, facilitating gli gene cluster expression, and an enzyme called GtmA (S-adenosylmethionine (SAM)-dependent bis-thiomethyltransferase)
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Sau khong 1 tun th da mnh c du hiu ni mn trn trn v cm, mnh cng khng qu ngc nhin bi v vitamin C c th khin c th nng trong v ni mn
Inactivation of DHODH in cancer cells with low GPX4 expression significantly increased intracellular lipid peroxidation, while in cancer cells with high GPX4 expression, DHODH inactivation synergized with inducers to enhance ferroptosis
