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A review in ScienceDirect found that obese patients are more likely to be deficient in vitamins A, D, B1, B9, B12, zinc, manganese, magnesium, and chromium, and that these deficiencies further impair carbohydrate and fat metabolism, creating what the authors describe as a vicious circle

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Eosinophils damage epithelial cells, the basement membrane, and nerve terminals via toxic MBP and eosinophil cationic proteins (ECP), which leads to edema of the nasal mucosa (116118)

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doi:10.1016/S0022-3476(94)70309-4

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