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Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those using diuretics concomitantly and the elderly

Reported Side Effects Epithalon is generally well-tolerated, with most users reporting minimal to no side effects

Although adverse side effects are considered tolerable, the likelihood increases in high-dose regimens and often involve the gastrointestinal tract by altering the composition of the microbiome 8,9,10,11

Nongbri PL (2013) The role of glucosinolates in the Arabidopsis/Piriformospora indica interaction

We typically recommend B12 therapy for individuals who have been diagnosed with B12 deficiency or who may be at risk due to factors such as age, certain medical conditions, or a vegan or vegetarian diet