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While the treatment with NP4 alone caused a strong production of ROS, the preincubation with NAC and subsequent treatment with NP4 showed a poor ROS generation (Fig

3.2 Correlation analysis of serum GPX-3 concentration and continuous variables at diagnosis in patients with AAV Serum GPX-3 concentration at diagnosis was inversely correlated with BVAS (r = 0.280, P = 0.018), VDI (r = 0.263, P = 0.029), and CRP (r = 0.261, P = 0.028) at diagnosis, whereas, it was positively correlated with haemoglobin (r = 0.255, P = 0.032), and serum albumin (r = 0.240, P = 0.045) at diagnosis, respectively

Interfaces 13 , 1470014709 (2021)

BUT, again, when ROS reaches higher pathological levels (so common), many problems arise, including (but not limited to)