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GSH depletion causes oxidative stress and lipid peroxidation To evaluate the downstream effects of GSH depletion, we measured soluble ROS in RPE cells treated with Cys 2 starvation, BSO, or erastin by flow cytometry using the fluorescent probe H 2 DCFDA

It followed Institutional Review Board (IRB) protocol for biomedical research and was registered at clinicaltrial can be used topically as a safe alternative mode of GSH delivery in the peripheral blood, the researchers noted

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Nevertheless, Tyurina et al

PMI: a DeltaPsim independent pharmacological regulator of mitophagy