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High doses may increase TMAO (trimethylamine-N-oxide), a compound linked to cardiovascular risk

Plenty of synthetic substances are safe

When mitochondrial function is disrupted by viral infections, chronic inflammation, or immune dysregulation, the body loses its ability to efficiently convert food into usable energy

Khera R, Murad MH, Chandar AK, Dulai PS, Wang Z, Prokop LJ, Loomba R, Camilleri M, Singh S (2016) Association of pharmacological treatments for obesity with weight loss and adverse events: a systematic review and Meta-analysis

This knowledge, combined with his father's second cancer diagnosis, compelled him to start Cymbiotika