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It is indicated as an adjunct to diet and exercise, either as monotherapy when metformin is not tolerated or as an add-on therapy with other diabetes medications

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12-14 A1C reductions of 0.4% to 0.9% were observed in studies of exenatide, with higher reductions achieved at the 10 mcg twice-daily dose

Albiglutide: a review of its use in patients with type 2 diabetes mellitus

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