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In a split-face randomized study (N=67) evaluating a 1% GHK-Cu serum over 12 weeks, 12% of participants reported transient erythema in the first two weeks, resolving spontaneously without discontinuation (Leyden et al., 2018, see related wound-healing data at NCBI)

Copper peptides should show some benefit by then

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, Mediator effects of parameters of inflammation and neurogenesis from a N-acetyl cysteine clinical-trial for bipolar depression, Acta Neuropsychiatr

Minimum acceptance is 99% purity by HPLC