In the double-blind, randomized, placebo-controlled, dose-escalation phase 1 study of ASHMI (600 mg, 1200 mg, 1800 mg), no grade 3 adverse events occurred, laboratory parameters before and after treatment remained within normal ranges, and no unexpected immunological changes were detected, supporting its safety and tolerability allowing for advancement to phase 2 study [99]
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Research suggests Long COVID and ME/CFS patients exhibit elevated oxidative stress and altered antioxidant pathways
[52] While elders are more sensitive to GH, and thus more susceptible to the side effects of replacement with rhGH, stimulating production and secretion of endogenous GH with Sermorelin offers the advantage of a more physiological approach to increasing GH pulsatility while reducing risk for side effects
Molina-Privado I, Rodriguez-Martinez M, Rebollo P, Martin-Perez D, Artiga MJ, Menarguez J, et al
