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Insured populations typically have lower obesity prevalence than the general public, limiting the scale of potential mortality improvement

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Annals of Hepatology

For those tracking their progress and wondering how fast semaglutide works and how long it takes , the clinical data shows measurable weight loss begins within the first four weeks, with the rate of loss accelerating as doses are titrated upward over the initial 16-20 weeks

Tip: Weigh yourself weekly at the same time of day, but don't obsess over daily fluctuations your weight naturally varies by 2-5 pounds day to day